Ganglionated Plexi Ablation Combined With Pulmonary Vein Isolation

Meshalkin Research Institute of Pathology of Circulation264 enrolled

Overview

The investigators have conducted a prospective, double-blind, randomized study to assess the comparative safety and efficacy of two different ablation strategies, PVI plus linear lesions (LL) versus PVI plus GP ablation, in patients with persistent or longstanding persistent AF. Results were assessed after follow-up of at least 3 years with the use of an implanted monitoring device (IMD).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

264

Conditions

Persistent Atrial Fibrillation

Interventions

Pulmonary vein isolationPROCEDURE

Ganglionated plexi ablationPROCEDURE

Linear Lesion AblationPROCEDURE

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Persistent and longstanding persistent AF Exclusion Criteria: * congestive heart failure * LV ejection fraction \< 35% * left atrial diameter \> 60 mm

Locations (1)

State Research Institute of CIrculation Pathology

Novosibirsk, Russia

Outcomes

Primary Outcomes

freedom of atrial tachyarrhythmia, including AF and atrial flutter/tachycardia

Time frame: 3 years

Data from ClinicalTrials.gov

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