Intraoperative Floppy Iris Syndrome in Korean Patients Taking α1-Adrenergic Receptor Antagonists

Samsung Medical Center150 enrolled

Overview

Intraoperative floppy iris syndrome (IFIS) is a recently described condition observed during cataract surgery. It has been hypothesized that irreversible atrophy of the iris dilator muscle associated with α1-adrenergic receptor antagonists (α1-ARA) is responsible for IFIS. However the prevalence of IFIS in Korean population is not reported. The purpose of this study is to evaluate the prevalence and clinical manifestations of IFIS in relation to iris anatomical change in Korean patients taking α1-ARA.

Study Type

OBSERVATIONAL

Enrollment

150

Conditions

Intraoperative Floppy Iris Syndrome

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * clinical diagnosis of cataract * korean patients Exclusion Criteria: * history of iridocyclitis, iris neovascularization, or prior iris surgery * traumatic cataracts, zonular dialysis, or cataracts associated with ocular disease (e.g., uveitis)

Outcomes

Primary Outcomes

occurrence of intraoperative floppy iris syndrome

Time frame: intraoperative

Data from ClinicalTrials.gov

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