Fat tissue from omenta, thigh and abdomen taken under anesthesia on subjects undergoing laparoscopic surgery, cholecystectomy, reflux surgery or gastric by-pass (GBP). Are there any difference in polymorphids and/or mRNA expression in genes significant for developing obesity, between normal weight and obese individuals, with or without diabetes typ 2 . Are there any difference in polymorphids and/or mRNA expression in different types of fat tissue
Study Type
OBSERVATIONAL
Enrollment
50
Ersta hospital
Stockholm, Stockholm County Council, Sweden
Karolinska Institutet, CMM
Stockholm, Sweden
Differences in polymorphids and/or mRNA expression in genes, significant for developing obesity and type 2 diabetes, between patients with normal weight and obesity
fat biopsy taken from abdomen, omenta and thigh at surgery
Time frame: approximatly 30 minutes after start of operation
Difference in polymorphids and/or mRNA expression in different types of fat tissue in patients with normal weight or obesity with or without diabetes type 2
fat biopsy; abdomen, omenta and thigh taken at surgery
Time frame: approximatly 30 minutes after start of operation
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