Lean Seafood Intake and Postprandial Metabolism

National Institute of Nutrition and Seafood Research, Norway27 enrolled

Overview

Despite numerous studies of meal components in humans, little is still known about how different meals influence on metabolism. The purpose of this study is to a gain knowledge of how a balanced test meal with either lean seafood (example:cod) or meat as the main protein source will: 1. affect the postprandial metabolism acutely (test-meal at beginning of the study) 2. affect the postprandial metabolism after 4 weeks controlled intervention (test meal at end of intervention period) 3. affect gut microbiota composition

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Enrollment

Conditions

Hyperlipidemias Nutritional and Metabolic Diseases Nutrition Disorders Metabolic Diseases Glucose Metabolism Disorders

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 18-65 years of age * Caucasian Exclusion Criteria: * Smoking * Diabetes * Hysterectomy * Abnormal bleeding last 6 months * Use of medication that affects lipid and glucose metabolism * Large (\>10%) alteration in body-weight the last 6 months * Chronic, metabolic or acute disease or major surgery within last 3 months * Dietary incompatibility with calcium supplementation and/ or seafood consumption (allergy, intolerance, dislike)

Outcomes

Primary Outcomes

Postprandial lipid measurement

Time frame: Change from baseline at 4 weeks

Secondary Outcomes

Postprandial glucose measurement