Carbohydrates are an integral component of sports nutrition. Providing carbohydrate (CHO) during exercise delays the onset of fatigue and improves exercise performance by maintaining high rates of CHO oxidation. Traditionally, glucose, or glucose polymers have been the preferential CHO source found in sports drinks. However, during the intestinal absorption of large amounts of glucose (\>1.2 g/min), sodium-dependent glucose transporters (SGLT1) may become fully saturated, potentially limiting the rate of exogenous CHO oxidation. In an effort to evade this limitation, research has suggested using multiple transportable carbohydrates in the composition of sports drinks. Multiple transportable carbohydrates are combinations of simple sugars that use different intestinal transporters during the absorption process. Ingesting multiple transportable carbohydrates may enhance the capacity for total intestinal CHO absorption, leading to an increase in the rate of exogenous CHO oxidation. Our purpose will be to examine the disaccharide sucrose in it's ability to provide exogenous fuel during and following prolonged exercise.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
DOUBLE
Enrollment
17
Various types of carbohydrate ingested during and following exercise
Maastricht University
Maastricht, Limburg, Netherlands
Exogenous carbohydrate oxidation rate (Part A)
Carbohydrate oxidation as measured by breath samples
Time frame: 0 min during trials 1-3
Endogenous carbohydrate oxidation (Part A)
endogenous carbohydrate oxidation as measured through breath samples during trials 1-3
Time frame: 0 min during trials 1-3
Glycogen utilization (Part B)
Glycogen utilization measured through a muscle biopsy sample at post (\~90 min), 3 and 6 h post exercise. Part B; trials 4-6.
Time frame: immediately post exercise (~90min), during trials 4-6
Exogenous carbohydrate oxidation rate (Part A)
Carbohydrate oxidation as measured by breath samples
Time frame: 30 min during trials 1-3
Exogenous carbohydrate oxidation rate (Part A)
Carbohydrate oxidation as measured by breath samples
Time frame: 60 min during trials 1-3
Exogenous carbohydrate oxidation rate (Part A)
Carbohydrate oxidation as measured by breath samples
Time frame: 90 min during trials 1-3
Exogenous carbohydrate oxidation rate (Part A)
Carbohydrate oxidation as measured by breath samples
Time frame: 120 min during trials 1-3
Exogenous carbohydrate oxidation rate (Part A)
Carbohydrate oxidation as measured by breath samples
Time frame: 150 min during trials 1-3
Exogenous carbohydrate oxidation rate (Part A)
Carbohydrate oxidation as measured by breath samples
Time frame: 180 min during trials 1-3
Endogenous carbohydrate oxidation (Part A)
endogenous carbohydrate oxidation as measured through breath samples during trials 1-3
Time frame: 30 min during trials 1-3
Endogenous carbohydrate oxidation (Part A)
endogenous carbohydrate oxidation as measured through breath samples during trials 1-3
Time frame: 60 min during trials 1-3
Endogenous carbohydrate oxidation (Part A)
endogenous carbohydrate oxidation as measured through breath samples during trials 1-3
Time frame: 90 min during trials 1-3
Endogenous carbohydrate oxidation (Part A)
endogenous carbohydrate oxidation as measured through breath samples during trials 1-3
Time frame: 120 min during trials 1-3
Endogenous carbohydrate oxidation (Part A)
endogenous carbohydrate oxidation as measured through breath samples during trials 1-3
Time frame: 150 min during trials 1-3
Endogenous carbohydrate oxidation (Part A)
endogenous carbohydrate oxidation as measured through breath samples during trials 1-3
Time frame: 180 min during trials 1-3
Glycogen utilization (Part B)
Glycogen utilization measured through a muscle biopsy sample at post (\~90 min), 3 and 6 h post exercise. Part B; trials 4-6.
Time frame: 3 h post exercise during trials 4-6
Glycogen utilization (Part B)
Glycogen utilization measured through a muscle biopsy sample at post (\~90 min), 3 and 6 h post exercise. Part B; trials 4-6.
Time frame: 6 h post exercise during trials 4-6
Indirect calorimetry (Part A)
Measurements of VO2, VCO2 and RER through indirect calorimetry measured every 30 minutes during trials 1-3
Time frame: every 30 min up to 180 min during trials 1-3
Plasma glucose
Plasma glucose measurements
Time frame: every 30 min up to 180 min during trials 1-6
Plasma insulin
plasma insulin measurements
Time frame: every 30 minutes up to 180 min during trials 1-6
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