Over the last years, a number of systems for continuous subcutaneous glucose monitoring have been marketed and are routinely used in patients with diabetes to obtain more detailed information about 24-hour glucose profiles. In the hospital, numerous factors influencing glycemic control and possibly leading to glucose excursions out of the desired range exist, e.g. interventions for which the patient has to remain fasting or medications such as corticosteroids or vasopressors. A reliable continuous glucose signal could help to observe levels of glycaemia not only at defined time-points but continuously, making it possible for physicians and nursing staff to better adjust antihyperglycemic therapy and to react before the patient is exposed to severe hypo- or hyperglycaemia. In the hospital setting, vascular access is granted in the majority of patients and could as well be used as an alternative site for continuous glucose monitoring. The aim of the present study is to assess accuracy of the glucose data obtained by means of an intravascular microdialysis-based CGM system against venous blood glucose reference measurements.
Study Type
OBSERVATIONAL
Enrollment
12
Glucose levels will be monitored by means of vascular microdialysis using the GlucoMen(R)Day system
Glucose levels will be monitored by means of vascular and subcutaneous microdialysis using the GlucoMen(R)Day system
Medical University of Graz, Dept. of Internal Medicine, Endocrinology and Metabolism
Graz, Austria
Point Accuracy of the microdialysis signal
MARD (mean absolute relative difference), MARE (mean absolute relative error), %Press analysis
Time frame: 72 hours
Rate accuracy of the microdialysis signal
R-EGA (rate error grid analysis) and P-EGA (point error grid analysis)
Time frame: 72 hours
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.