The optimal strategy for catheter ablation of persistent atrial fibrillation is not clearly defined. This study investigates if Complex Fractionated Atrial Electrogram (CFAE) ablation in addition to pulmonary vein isolation and linear ablations improves single procedural success rate over a 12 month follow up period.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
120
In this arm, catheter ablation would be performed in the left atrium and would include pulmonary vein isolation and linear ablations (roof and mitral isthmus lines)
In this arm, catheter ablation would be performed in the left atrium, including pulmonary vein isolation, linear ablations (roof and mitral isthmus lines) and Complex Fractionated Atrial Electrograms (CFAE) ablation.
Royal Bournemouth Hospital
Bournemouth, United Kingdom
John Radcliffe Hospital
Oxford, United Kingdom
Single procedural success rate (free from AF off anti-arrhythmic drugs)
Time frame: 12 MONTHS
Multiple procedure success rate
Time frame: 12 months after last ablation
Complication rate
Time frame: 30 days of procedure
Percentage of AF termination
This information will be recorded immediately after the procedure.
Time frame: Time 0
recurrence of atrial fibrillation or organised atrial tachycardia
Time frame: 12 months after the last procedure
Ablation time
This information will be recorded immediately after the procedure.
Time frame: Time 0
Procedure time
This information will be recorded immediately after the procedure
Time frame: Time 0
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.