The purpose of this study is to determine if there are differences in clinical events, i.e bleeding with associated morbidity, if thromboprophylaxis with LMWH (Low Molecular Weight Heparin) is initiated before or after surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
80
All patients receive injections with either 5000IU dalteparin or saline in the same volume the evening before surgery. All patients receive 5000IU dalteparin 6 hours after surgery and every day from day 2 until day 35.
Martina Hansen's Hospital
Sandvika, Gjettum, Norway
total blood loss
measured blood loss during surgery and in wound drains
Time frame: during and after surgery
transfusion requirements
number of units packed red blood cells
Time frame: during and after surgery
incidence of bleeding events
excessive bleeding, wound hematoma, wound secretion, other bleeding events
Time frame: during and after surgery
other complications
all other complications related to surgery
Time frame: during and after surgery
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