Piperacillin/Tazobactam for Empirical Therapy of Febrile Neutropenia

Microbiologic success rate

Microbiologic success includes eradication, suspected eradication, and super-infection. 1. Eradication or Presumed eradication: the baseline pathogens no longer present on the culture performed after completion of treatment. If no way to collect biologic sample(s) after treatment;, e.g. sputum, a presumed eradication will be concluded 2. No eradication: one or more baseline pathogens were persistent 3. Relapse: the baseline pathogens transient absence reappeared during the therapy 4. Alternative: the baseline pathogens were eradicated, but new ones appeared without any clinical signs and symptoms 5. Re-infection: the baseline pathogens were eradicated, but new ones appeared with clinical signs and symptoms.

Time frame: 3 weeks after beginning of empirical therapy

Adverse effect

The number of patients developed unexpected medical information at the 3 weeks after beginning of empirical therapy.

Time frame: 3 weeks after beginning of empirical therapy

Cost of drug and therapy

Time frame: 3 weeks after beginning of empirical therapy