Study on the Effect of Intravenous Ascorbic Acid on Intraoperative Blood Loss in Women With Uterine Myoma

Seoul National University Hospital50 enrolled

Overview

The investigators want to know whether the intravenous ascorbic acid would reduce the blood loss during laparoscopic myoma surgery. The investigators randomized patients into intravenous ascorbic acid group and placebo group and examined the blood loss in both groups.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Uterine Leiomyoma

Interventions

ascorbic acidDRUG

ascorbic acid 2g in normal saline 500ml IV start 30min before the operation and infusion for 2 hour

Normal salineDRUG

normal saline 500ml IV

Eligibility

Sex: FEMALE

Medical Language ↔ Plain English

Inclusion Criteria: * uterine myoma * be planning to laparoscopic myomectomy * images ; the number of myoma \<4 * images ; the diameter of the largest myoma \<9cm Exclusion Criteria: * be planning other surgery in addition to laparoscopy * clinically significant coagulation abnormality

Locations (1)

Seoul National University Bundang Hospital

Gyeongg-ido, South Korea

Outcomes

Primary Outcomes

blood loss

Time frame: during laparoscopic myomectomy

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.