This clinical trial is a multicentric prospective study to assess the clinical and prognostic value of sarcopenia in patients older than 70 years with diffuse large B-cell lymphoma.
Sarcopenia status is assessed by CT scan imaging on the overall survival at 18 months in patients older than 70 years with diffuse large B-cell lymphoma treated by R-CHOP.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
98
To attest the muscular strength: hand grip test, balance test, up and go test
Centre Henri Becquerel
Rouen, France
progression free survival
Time frame: at 18 months
progression free survival
Time frame: at 24 months
rate of over grade 2 toxicities
Time frame: at the first and second courses of chemotherapy (day 21 and day 42)
determination of both molecular subtypes GCB and ABC
according DASL technology (c-DNA mediated annealing selection extension and ligation)
Time frame: at 24 months
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