The purpose of the study is to evaluate food factors related to colonically derived regulation of glucose metabolism (and related parameters) and satiety using a semi-acute meal study in healthy subjects as experimental model.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Enrollment
21
Applied Nutrition and Food Chemistry, Lund University
Lund, Sweden
Differences in concentration of risk markers in blood, measured post-prandial after a breakfast meal.
Variables (blood glucose, insulin, incretin, inflammatory markers, markers of colonic fermentation) are measured after two-weeks ingestion of test products. The experimental day is terminated after a lunch meal.
Time frame: Post-prandially after breakfast, 0-210 min
voluntary energy intake
Energy intake at lunch is measured after two-weeks ingestion of test products. The experimental day is terminated after the lunch meal.
Time frame: Post-prandially after breakfast, 0-210 min
Subjective satiety
The subjective sensation of satiety, hunger and desire to eat is measured using a (VAS) questionnaire.
Time frame: post-prandially after breakfast, 0-210 min
Differences in gut microbiota
The effect on gut microbiota of 14 days intake of test- and reference product are investigated in faecal samples.
Time frame: Faecal samples are collected after 14 days intake of test- and reference product
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