Effects of Postoperative Residual Paralysis on Hospital Costs

Massachusetts General Hospital3,000 enrolled

Overview

This is a secondary analysis of a previously performed prospective, observer-blinded, observational study at Massachusetts General Hospital. The primary aim of this study is to evaluate the effects of residual paralysis at admission to the post-anesthesia care unit (PACU) on total costs of hospital care. Secondary analyses will be conducted to evaluate the effects of postoperative residual paralysis on potential cost-influencing factors, i.e. incidence of minor and major postoperative respiratory complications, hospital length of stay (LOS), unplanned intensive care unit (ICU) admission rate, as well as length of stay in the PACU.

Study Type

OBSERVATIONAL

Enrollment

3,000

Conditions

Residual Paralysis, Post-Anesthesia

Interventions

Quantitative measurement of neuromuscular transmissionPROCEDURE

Quantitative measurement of neuromuscular transmission with train-of-four watches.

Eligibility

Medical Language ↔ Plain English

Inclusion Criteria: * Each subject has been given non-depolarizing neuromuscular blocking agents as part of general anesthesia. * Each subject must be at least 18 years of age * Train-of-four monitoring in the post-anesthesia care unit Exclusion Criteria: * The subject is scheduled to be transferred to an intensive care unit after surgery. * Children and pregnant women

Outcomes

Primary Outcomes

Hospital costs

Time frame: Patients will be followed from date of admission to date of hospital discharge, an expected 2 days to 4 weeks

Secondary Outcomes

Hospital Length of Stay

Time frame: within 100 days after surgery