Clinical Trial of Motilitone on Gastric Motor Function in Healthy Volunteers

Inclusion Criteria: * no gastrointestinal symptoms * no organic lesion such as gastrointestinal malignancies, erosive esophagitis, reflux esophagitis, erosive gastroduodenitis, gastric or duodenal ulceration after having normal upper abdominal endoscopy * written informed consent Exclusion Criteria: * pregnant, breast-feeding female,those of childbearing age who were not using an approved method of contraception * history of abdominal surgery that may influence gastrointestinal motility * gastrointestinal hemorrhage, mechanical ileus, enterobrosis * irritable bowel syndrome, inflammatory bowel disease * severe disturbance of liver, kidney, heart,lung,blood and endocrine * psychoneurosis, alcoholism, drug dependence * medications that may alter evaluation of Motilitone including antibiotics,corticosteroids, NSAID within 1 month, prokinetics, H2 blocker, PPI, anticolines, erythromycin, antidepressive agents withing 2weeks