The recent dramatic increase in obesity has been linked to a reduction of dietary fibre intake. We hypothesized that supplementing the diet of overweight and obesity adults with pulse fibre will improve their metabolic status, chiefly defined as greater weight loss. Other metabolic health improvements may include improved glucose control and reduced inflammatory markers.
The main objective of our study is to assess the effects of pulse fibre supplementation on weight loss in an overweight and obese adult population. Primary objective - To determine the effects of a 12 week intake of 15g/day of pea hull fibre on weight loss supported by body composition measures. Secondary objective - To measure glucose control and appetite regulation in overweight and obese adults consuming 15g/day of pea hull fibre compared to a placebo control with the use of plasma HbA1c and an oral glucose tolerance test (OGTT). Tertiary objective - To examine mechanisms of action of pulse fibre supplementation by determining the impact of pulse fibre supplementation on gut microbiota, serum metabolomics and fecal short-chain fatty acid and bile acid concentrations.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
53
Yellow pea hull fibre incorporated into a biscuit at 5 g/serving.
Control biscuit with no yellow pea hull fibre.
University of Calgary
Calgary, Alberta, Canada
Change in Fat Mass at 12 Weeks
Value at 12 weeks minus value at baseline assessed with dual energy x-ray absorptiometry.
Time frame: Value at 12 weeks minus value at baseline
HbA1c at 12 Weeks
Assessed via HbA1c
Time frame: 12 weeks
Change in Objective Appetite at 12 Weeks
Value at 12 weeks minus baseline energy intake during weighed lunch buffet.
Time frame: 12 weeks minus baseline
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