Improving arm and hand function after stroke has been difficult to achieve within the rehabilitation service provided in the acute stage often due to the limited resource in health care. While spontaneous recovery plateaus after 6 months, the prolonged disability affects quality of life and social participation in stroke survivors. This study is aimed at improving chronic motor impairment arm and hand impairment by providing the intervention with intensive training schedule. This study will compare two types of rehabilitation intervention using a randomized controlled trial. Measurements also will be taken on various brain functions non-invasively to help discover how each of the intervention strategies works differently to repair the brain.
After unilateral stroke, incomplete recovery of arm and hand movement is common and its long-lasting negative effects include increased care giving costs and overall reduced quality of life. Recent evidence suggests that a novel behavioral intervention could improve motor functions in sub-acute patients with added benefits in cognitive and brain functions. However few studies have addressed whether chronic stage patients can also benefit from the intervention and how brain plasticity works over the course of rehabilitation. This study will investigate the benefits of two types of intervention methods that are extendable for community-based intervention services in the future. It also will examine changes in integrity of motions before and after the intervention. Further comparisons between brain functions and structure will be made using magnetoencephalography (MEG) and magnetic resonance imaging (MRI), non-invasively. These behavioural and physiological measures will inform the mechanisms of stroke recovery and training.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
29
Music Supported Rehabilitation -using musical exercises to improve hand and arm motor functioning.
-GRASP (Graded Repetitive Arm Supplementary Program-developed Janice Eng, PhD, PT/OT Jocelyn Harris, PhD, OT, Andrew Dawson, MD, FRCP, Bill Miller, PhD, OT) protocol will be used to improve arm and hand function in people living with stroke.
Baycrest Centre for Geriatric Care
Toronto, Ontario, Canada
Change in performance on Action Research Arm Test
Changes in performance from baseline to post-intervention at 5 weeks, to post-intervention at 10 weeks, and to follow-up at 4 mos will be measured.
Time frame: Baseline, post-5-weeks, post-10-weeks, and 4-month-follow-up
Change in performance on Chedoke Arm and Hand Inventory
Changes in performance from baseline to post-intervention at 5 weeks, to post-intervention at 10 weeks, and to follow-up at 4 mos will be measured.
Time frame: Baseline, post-5-weeks, post-10-weeks, and 4-month-follow-up
Change in status on Stroke Impact Scale
Changes in performance from baseline to post-intervention at 5 weeks, to post-intervention at 10 weeks, and to follow-up at 4 mos will be measured.
Time frame: Baseline, post-5-weeks, post-10-weeks, and 4-month-follow-up
Brain structure
Structural MRI
Time frame: Pre, post-5-weeks, post-10-weeks, and 4-month-follow-up
Brain Function
Brain functions related to sensory and motor systems assessed by MEG
Time frame: Baseline, post-5-weeks, post-10-weeks, and 4-month-follow-up
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.