The aim of the study is to investigate how the retina adapts to different metabolic challenges, e.g. chronic systemic hypoxia, hyperglycemia, special training conditions or diets as well as transient changes in the content of oxygen and glucose in the blood.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Masking
NONE
Enrollment
120
Department of Ophthalmology, Glostrup University Hospital
Glostrup Municipality, Denmark
RECRUITINGRetinal vessel diameters during hyperoxia
Measurement of retinal vessel diameters before, during and after hyperoxic stimulation.
Time frame: Before hyperoxia, after 15 minutes of hyperoxia, 30 minutes after ending hyperoxia
Retinal perfusion velocities during hyperoxia
Measurement of retinal perfusion velocities before, during and after hyperoxic stimulation.
Time frame: Before hyperoxia, after 15 minutes of hyperoxia, 30 minutes after ending hyperoxia
Retinal oximetry during hyperoxia
Measurement of retinal oximetry status before, during and after hyperoxic stimulation.
Time frame: Before hyperoxia, after 15 minutes of hyperoxia, 30 minutes after ending hyperoxia
Retinal vessel diameters during hyperglycemia
Measurement of retinal vessel diameters before, during and after hyperglycemic stimulation.
Time frame: Before glucose ingestion, every 30 minutes for 3 hours following oral glucose load
Retinal perfusion during hyperglycemia
Measurement of retinal perfusion velocities before, during and after hyperglycemic stimulation.
Time frame: Before glucose ingestion, every 30 minutes for 3 hours following oral glucose load
Retinal oximetry during hyperglycemia
Measurement of retinal oximetry status before, during and after hyperglycemic stimulation.
Time frame: Before glucose ingestion, every 30 minutes for 3 hours following oral glucose load
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