Renal Function During Laparoscopic Surgery

Catholic University of the Sacred Heart60 enrolled

Overview

Aim of this study was to investigate the cardiac and renal responses to the administration of different amount of crystalloids, with and without dopamine, during gynaecological laparoscopic surgery.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Intra Operative Fluid Management

Interventions

DopamineDRUG

Eligibility

Sex: FEMALEMin age: 24 YearsMax age: 42 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ASA I * age 24-42 * patients undergoing gynaecological laparoscopy Exclusion Criteria: * cardiovascular diseases * renal and endocrine disorders * obesity (BMI \> 30 Kg/m2) * the assumption of drugs that could interfere with renal parameters considered in the study

Locations (1)

Catholic University of the sacred Heart

Rome, Rome, Italy

Outcomes

Primary Outcomes

estimated glomerular filtration rate, tissue Doppler imaging, E/Ea

EGFr, tissue Doppler imaging and E/Ea are registered after the induction of pneumoperitoneum and Trendelemburg position, and compared to those registered before the induction of anesthesia.

Time frame: patients will be followed for the duration of surgery, an expected average of 3 hours

Secondary Outcomes

total intra operative diuresis (TID)

TID will be measured at the end of surgery

Time frame: patients will be followed for the duration of surgery, an expected average of 3 hours

Data from ClinicalTrials.gov

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