This observational study will evaluate the patterns of disease progression in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) harbouring EGFR activating mutations receiving Tarceva (erlotinib) as first-line treatment. Patients will be followed for up to 12 months after progression of disease.
Study Type
OBSERVATIONAL
Enrollment
144
Progression-free survival (time from initiation of treatment to disease progression or death of any cause) in correlation with localization of progression and clinical tumor characteristics
Time frame: 3 years
Objective response rate, tumor assessments according to RECIST v1.1 criteria
Time frame: 3 years
One-year overall survival (from initiation of treatment to 12 months after disease progression)
Time frame: 3 years
Time to progression
Time frame: 3 years
Exposure (dosage/duration) with first-line Tarceva in clinical practice
Time frame: 3 years
Safety: Incidence of adverse events
Time frame: 3 years
Velocity of progression (disease flares) after cessation of treatment with Tarceva following disease progression
Time frame: 3 years
Treatments used after disease progression in clinical practice
Time frame: 3 years
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