Perioperative Pregabalin and Continuous Wound Infusion for Pain Control Following Thoracotomy

Attikon Hospital45 enrolled

Overview

The purpose of this study is to assess the efficacy of pregabalin or pregabalin and continuous wound infusion versus placebo for analgesia following thoracotomy

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Post-thoracotomy Pain

Interventions

Pregabalin and normal saline infusion, PRGDRUG

Pregabalin and ropivacaine 02% infusionDRUG

Placebo drug, normal saline infusionDRUG

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients scheduled for a thoracotomy, Exclusion Criteria: * age \>70 years * BMI \> 30 * preoperative Hb \< 10 mg/dL * preexistent chronic pain * neurologic disease * chronic assumption of alcohol * treatment with analgesics, anxiolytics, sedatives, antidepressants, or calcium channel inhibitors

Locations (1)

Attikon Hospital

Athens, Greece

Outcomes

Primary Outcomes

Pain control

Time frame: 5 days postoperatively

Secondary Outcomes

morphine consumption

Time frame: 3 days postoperatively

Data from ClinicalTrials.gov

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