This pilot study is aimed at assessing the acute effect of several combinations of lipids differing in their fatty acid composition on glucagon-like-peptide (GLP)-2 and GLP-1 secretion in healthy subjects.
In this study, the investigators aim to investigate the effect of various lipid types on GLP-2 and GLP-1 secretion. This will allow to determine the importance of lipids in nutritional solutions. Moreover, this will allow us to assess whether existing clinical formulas can be improved in order to stimulate GLP-2 and accelerate intestinal recovery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Enrollment
18
Intake of meals characterized by lipid composition
Nestlé CDU / Metabolic Unit
Lausanne, Switzerland
GLP-2 and GLP-1 kinetics
GLP-2 and GLP-1 are measured using Elisa
Time frame: changes from baseline to 4 hours following meal intake
Intestinal and metabolic hormones
Those hormones will be measured based on enzymatic technics
Time frame: Changes from baseline to 4 hours following meal intake
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.