Effects of Dietary Nitrate on Age-related Vascular Function

Heinrich-Heine University, Duesseldorf20 enrolled

Overview

Purpose of the study is to characterize the chronic effect of dietary nitrate on vascular function in healthy volunteers with particular emphasis on age-related alterations.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

Conditions

Endothelial Dysfunction

Interventions

NitrateDIETARY_SUPPLEMENT

Dietary Supplement

PlaceboDIETARY_SUPPLEMENT

Dietary Supplement

Eligibility

Sex: ALLMin age: 55 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: \>55 Years Healthy Exclusion Criteria: known cardiovascular disease

Locations (1)

Heinrich-Heine-University

Düsseldorf, North Rhine-Westphalia, Germany

Outcomes

Primary Outcomes

Endothelial function measured by flow-mediated dilation (FMD)

The effect of dietary nitrate on endothelial function as measured by flow-mediated dilation (FMD) after forearm ischemia and reperfusion.

Time frame: 30 days

Data from ClinicalTrials.gov

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