Coagulation and Fibrinolysis as Virulence Factors for Invasive Staphylococcus Aureus and Streptococcus Infections

Universitaire Ziekenhuizen KU Leuven89 enrolled

Overview

the aim of this study is to investigate the role of staphylokinase, streptokinase and MMP activation in invasive staphylococcal and streptococcal infections.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Infective Endocarditis Necrotizing Fasciitis

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * all patients that undergo surgical treatment for invasive streptococcal or staphylococcal infections, including acute infective endocarditis and necrotizing fasciitis, from the UZ Leuven University Hospital Exclusion Criteria: * none

Locations (1)

UZ Leuven University Hospital

Leuven, Belgium

Outcomes

Primary Outcomes

proteolytic activity

Time frame: 1 day (on date of surgery (tissue sample))

Data from ClinicalTrials.gov

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