The purpose of this study is to determine whether an educational intervention given towards health care providers working in primary health care centers can reduce inappropriate prescribing in the elderly patient and thus reduce number and length of drug-related hospitalizations as well as number of emergency department visits in this patient group.
Inappropriate medication in the elderly patient leads to substantial morbidity, possibly causing up to 20% of hospitalizations in this patient group (1). To improve prescribing and thus reduce undesired drug effects is a great challenge for doctors and nurses in primary health care. Performance of drug utilization reviews is recommended in order to reduce the negative impact of inappropriate prescribing in the elderly. However, scientific evidence on their efficacy is lacking, especially regarding patient-related health outcomes (2,3). Most studies are carried out in inpatient care, making it difficult to draw conclusions regarding primary health care (2). Moreover, studies in this scientific field diverge regarding the content and structure of drug utilization reviews, which implies that comparison between studies becomes challenging, if not impossible. This trial aims at educating health care providers in how to perform drug utilization reviews, and to help them implement theory into practice.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
69
Primary health care centers (PHCC) in the intervention group will be visited twice by a pharmacist within a period of three months. At the first visit, an educational intervention will focus on two properties: on the one hand, feed-back of actual patient data of the PHCC illustrating the primary-health-care-specific characteristics of inappropriate prescribing in the elderly patient will be given. Education of relevant subjects will be given in relation to detected problems. On the other hand, a clinical routine regarding the performance of drug utilization reviews will be developed in cooperation with the health care providers. At the second visit 3 months later, the developed concept will be critically reviewed and eventually developed further.
Centre for Family Medicine, Dept of Neurobiology, Care sciences and Society, Karolinska Institutet
Huddinge, Sweden
Composite outcome: Unplanned hospitalisation or emergency department visit
Time frame: 9 months
Unplanned hospitalisation
Time frame: 9 months
Emergency department visit
Time frame: 9 months
Length of hospital stay
Time frame: 9 months
All cause mortality
Time frame: 9 months
Number of drug utilization reviews
Time frame: 9 months
Number of patients with polypharmacy
polypharmacy: 5-9 drugs/patient excessive polypharmacy: 10 and more drugs/patient
Time frame: 9 months
Inappropriate drug use according to national guidelines
see link
Time frame: 9 months
Number of patients with contraindicated drugs regarding renal function
Time frame: 9 months
Number of drugs with inappropriate drug dose regarding renal function
Time frame: 9 months
Number of drug interactions
Time frame: 9 months
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