Exploratory study with double-blind, randomized, placebo-controlled, full cross-over design. The main objective is to identify one or two flour compositions in a carbohydrate-based food that produce a significant difference (alpha =0.2) in the time to reach 50% of cumulative absorption of exogenous glucose compared to the control.
Twelve volunteers will participate in the study; each person will be studied on three different occasions at least one week apart, consuming the three different test products in a randomized order. Test products are carbohydrate-based food made from different flour mixes differing in their expected rate of intestinal starch digestion. The products are labeled with 13C starch.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Enrollment
12
Carbohydrate based food
Carbohydrate based food
Carbohydrate based food
QPS
Groningen, Hanzeplein 1, Netherlands
Rate of appearance of exogenous glucose (RaE) based on the dual isotope technique.
Time frame: Measured during 360 min for 3 periods
Total blood glucose and insulin
Time frame: Measured during 360 min for 3 periods
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