Phase I Study to Assess the Effect on Healthy Male Volunteers of Ketoconazole on the Pharmacokinetics of a Single Dose of AZD5069 Administered Orally.

Inclusion Criteria: * Healthy male volunteers aged 18 to 50 years (inclusive). * Veins suitable for cannulation or repeated venipuncture. * Healthy volunteers with neutrophil counts within the laboratory normal reference range at Screening * Body mass index (BMI) ≥18.0 and ≤30.0 kg/m2 calculated from height and weight at screening; minimum weight 50 kg and maximum weight 100 kg. * Non-smokers or ex-smokers with no smoking history for the last 3 months prior to screening and a smoking history of less than 10 pack years (1 pack year = tobacco consumption corresponding to 20 cigarettes smoked per day for 1 year) at screening. Exclusion Criteria: * Healthy volunteers with latent tuberculosis as suggested by their history and judged by the Investigator * Healthy volunteers who belong to a high-risk group for HIV infection. * Known or suspected history of significant drug abuse as judged by the Investigator. * History of alcohol abuse or excessive intake of alcohol as judged by the Investigator. * Plasma donation within 1 month of screening or any blood donation/blood loss \>500 mL during the 3 months and/or 1350 mL within the 12 months prior to screening.