A previous study demonstrated topical lidocaine spray on the larynx and the trachea is effective in reducing hemodynamic response to laryngoscopy and endotracheal intubation. In clinical practice, blind oropharyngeal application of lidocaine without aiding direct laryngoscopy can not assured that sprayed lidocaine effectively reaches the larynx and trachea. Therefore, direct laryngoscopy should be necessary to reach topical lidocaine to correct sites. Unfortunately, direct laryngoscopy itself can affect hemodynamics during spraying lidocaine. In this study, we will investigate an effect of lidocaine sprayed on direct laryngoscopy and the tracheal mucosa on hemodynamic change throughout intubation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
80
0.9% normal saline was applied to trachea and laryngoscope blade
10% Lidocaine was applied to the laryngoscope blade and 0.9% normal saline was applied to the trachea.
0.9% normal saline was applied to the laryngoscope blade and 10% Lidocaine was applied on trachea.
10% Lidocaine was applied on laryngoscope blade and trachea.
Seoul National University Hospital
Seoul, Seoul, South Korea
RECRUITINGmean blood pressure, heart rate
Time frame: baseline, at laryngoscope insertion, 60s after laryngoscope insertion, during intubation, one, two, three min after endotracheal intubation
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