Dexamethasone Added to Levobupivacaine Improves Postoperative Analgesia

University Hospital Dubrava55 enrolled

Overview

Adding dexamethasone to local anesthetic will significantly prolong duration of brachial plexus anesthesia and analgesia.

Operations of upper extremities are often performed in regional anesthesia blocks. Single-injection blocks are effective, but time limited. Adding 4mg of dexamethasone to 0.5% levobupivacaine will significantly prolong duration of brachial plexus anesthesia and analgesia for fracture operations of upper extremity. This effect will result in less opioid use postoperatively.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Brachial Plexus Anesthesia Analgesia

Interventions

supraclavicular brachial plexus blockPROCEDURE

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients aged 18 years or older * ASA (American Society of Anesthesiologists) physical status I, II or III Exclusion Criteria: * refusal of the patients to give informed consent * preexisting coagulation disorders * local infection at the site of the block * neuropathy * drug or alcohol abusers * known allergy to the drug used in study * operation time exceeding six hours

Locations (1)

Clinical Hospital Dubrava

Zagreb, Croatia

Outcomes

Primary Outcomes

duration of analgesia

Duration of analgesia after supraclavicular block

Time frame: 24 hour postoperatively

Secondary Outcomes

postoperative analgesic consumption

Time frame: 24 hour

Data from ClinicalTrials.gov

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