Packing of Perianal Abscess Cavities Trial: A Randomised Multicentre Trial Comparing Packing With Non-packing of the Abscess Cavity

North Western Research Collaborative300 enrolled

Overview

The aim of this study is to compare the effect of packing and non-packing on the healing rate of perianal abscess cavities. Secondary objectives are to assess quality of life, cost effectiveness and rate of abscess recurrence and fistula-in-ano formation. If there is no difference in time to healing and non-packing is shown to be safe, acceptable to the patient and cost effective, this approach may become more widely accepted.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Masking

NONE

Enrollment

300

Conditions

Perianal Abscess

Interventions

Packing of abscess cavityOTHER

External dressingOTHER

Application of external dressing whilst abscess cavity heals

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical diagnosis of acute primary perianal abscess * Have undergone surgical incision and drainage as an emergency Exclusion Criteria: * The abscess is the sequelae of concurrent disease or trauma * Fourniers gangrene is suspected * Unable to give informed consent

Outcomes

Primary Outcomes

Time to wound healing in days, defined as complete epithelialisation of the abscess cavity.

time to healing will be assessed in days

Time frame: 1 day to 6 weeks

Secondary Outcomes

Quality of life scores as determined by the Euro QoL EQ-5D-3L

Quality of life scores as determined by the Euro QoL EQ-5D-3L will be measured at 10-14 days following incision and drainage of abscess

Time frame: 10 to 14 days

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.