The Effect of Anodal tDCS on Motor Learning in Multiple Sclerosis

Hasselt University31 enrolled

Overview

The current study investigates the effects of tDCS in patients with multiple sclerosis (MS). The investigators hypothesize that anodal tDCS will increase motor performance in patients with MS.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Anodal tDCS Recruitment Curves

Interventions

Transcranial Direct Current Stimulation (tDCS) (Neuroconn DC-stimulator)DEVICE

The anode will be fixed over the primary motor cortex. The cathode will be fixed over the contralateral supraorbital region.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * at least 18 years old * male and female Exclusion Criteria: * relapse in the last 3 months * when not suitable for tDCS (screening) * if TMS measures can not be completed

Outcomes

Primary Outcomes

Motor performance on a unimanual sequence learning task

Patients were instructed to perform a unimanual sequence-learning task consisting of sequential finger presses. The following parameters were measured: Correct sequences/mean inter tap interval (ITI), percentage correct key presses/mean ITI, percentage correct sequences, percentage correct key presses, mean ITI, and mean correct sequences in the performance interval.

Time frame: Baseline, during training and POST (30 min after baseline) intervention

Data from ClinicalTrials.gov

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