The Effect of tDCS on Motor Performance and Cortical Excitability

Hasselt University30 enrolled

Overview

In this study the effect of tDCS intensity on motor performance and corticospinal (CS) excitability is evaluated. The investigators expect that a positive relationship between current intensity and motor performance/CS excitability.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Cortical Excitability Motor Performance tDCS

Interventions

transcranial direct current stimulation (tDCS) (NeuroConn DC-stimulator)DEVICE

The anode is fixed on the primary cortex and the cathode will be fixed on the contralateral supraorbital region.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: \- Healthy subjects Exclusion Criteria: * Contraindications for tDCS/TMS * TMS measurements have to be possible

Outcomes

Primary Outcomes

Change in motor performance

motor performance is assessed using different reaction time paradigms (simple reaction time, choice reaction time). This is done at baseline and immediately after the intervention (30 min after baseline)

Time frame: Baseline and POST (30 min after baseline) intervention

Change in cortical excitability

Cortical excitability is measured using trancranial magnetic stimulation (TMS) measuring muscle evoked potentials (MEPs) at baseline and POST (30 min after baseline).

Time frame: Baseline and POST (30 min after baseline) intervention

Data from ClinicalTrials.gov

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