Osteoarthritis patients undergoing primary hip and knee replacement are followed-up and changes in their glucose metabolism and other metabolic parameters (obesity, cholesterol levels) are examined. Persistent postoperative pain is examined as secondary outcome.
Glucose metabolism disorders (diabetes and pre-diabetes) and metabolic syndrome are common in joint replacement recipients. Improved physical activity following joint replacement could lead to better glucose control in diabetes and ameliorate impaired glucose and cholesterol levels. In this study patients previously recruited to "Perioperative Hyperglycaemia in Primary Total Hip and Knee Replacement" study are being followed-up for one year in order to analyze if joint replacements have an effect on these metabolic abnormalities. In addition, the effect of glucose metabolism disorders on occurrence of persistent pain after surgery is analyzed.
Study Type
OBSERVATIONAL
Enrollment
155
Coxa, Hospital for Joint Replacement
Tampere, Finland
Change in glucose tolerance, measured using oral glucose tolerance test
The patients are grouped into three groups that are evaluated 12, 18 and ca. 24 months after surgery.
Time frame: Baseline and 12-24 months after surgery
Change in cholesterol levels (HDL, LDL, triglycerides)
Time frame: Baseline and 12-24 months after surgery
Prolonged postoperative pain
Assessed using visual analog scale. Patients are divided in three groups that are evaluated 12, 18 and 24 months after surgery.
Time frame: 12-24 months after surgery
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.