Study to See if Platelet Transfusion Stop or Lessen the Effect of the Drug on Platelets

Inclusion Criteria: * Provision of signed and dated, written informed consent prior to any study specific procedures * Healthy male and/or female volunteers aged 18 to 50 years, inclusive, with suitable veins for cannulation or repeated venipuncture. (Healthy as determined by medical history and physical examination, laboratory parameters, electrocardiogram (ECG) perform * Have a body mass index (BMI) between 18 and 35 kg/m2 (inclusive) and weigh at least 50 kg and no more than 120 kg Exclusion Criteria: * ADP induced platelet aggregation \<60% prior to platelet apheresis * History of peptic ulcer disease Healthy volunteers with a propensity to bleed (eg, due to recent trauma, recent surgery, active or recent gastrointestinal bleeding or moderate hepatic impairment) * Any clinically significant illness, medical/surgical procedure or trauma within 4 weeks of the first administration of the investigational product * Current smokers, those who have smoked or used nicotine products within the previous 3 months and those who tested positive for cotinine at screening or at admission to the study center