Preoperative Biliary Drainage for the Lower Malignant Obstructive Jaundice

Tianjin Medical University Cancer Institute and Hospital136 enrolled

Overview

Patients with the lower malignant obstructive jaundice planned to do the pancreaticoduodenectomy, receiving preoperative biliary drainage or early surgery (without preoperative biliary drainage), both groups has the similar surgical morbidity, no statistics significance.

Patients with the lower malignant obstructive jaundice divided into two groups:early surgery, preoperative biliary drainage + surgery.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

136

Conditions

Postoperative Complications

Interventions

preoperative biliary drainagePROCEDURE

percutaneous preoperative biliary drainage guided by CT

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with the lower malignant obstructive jaundice * Total bilirubin: 150-350 umol/L Exclusion Criteria: * age less than 18 * emergency operation * biliary tract stent placed * past history of operation on pancreas * intraoperative unresectable tumor with pancreaticoduodenectomy * unresectable tumor or potential resectable tumor with pancreaticoduodenectomy

Outcomes

Primary Outcomes

the difference in postoperative morbidity

the difference in postoperative morbidity between two groups (preoperative biliary drainage or early surgery (without preoperative biliary drainage))

Time frame: 12 weeks postoperation

Data from ClinicalTrials.gov

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