The primary objective of this study was to determine the ability of cardiac magnetic resonance (CMR) to identify cardiac involvement in patients with sarcoidosis. Patients were to undergo CMR in addition to routine clinical evaluation.
In patients with sarcoidosis, cardiac death is a leading cause of mortality which may represent unrecognized cardiac involvement. Cardiovascular magnetic resonance (CMR) can detect cardiac involvement including minute amounts of myocardial damage. Therefore, the objective of this study was to determine the usefulness of CMR and compare it with standard clinical evaluation for cardiac involvement. Patients with documented extracardiac sarcoidosis or clinically suspected cardiac sarcoidosis will be enrolled.
Study Type
OBSERVATIONAL
Enrollment
27,000
Duke University Medical Center
Durham, North Carolina, United States
RECRUITINGcardiac mortality
Time frame: > 1year
arrhythmic death
Time frame: > 1year
Pulmonary mortality
only in subset of patients with pulmonary sarcoidosis
Time frame: > 1year
all-cause mortality
Time frame: > 1year
arrhythmic events
Time frame: > 1year
Pulmonary Transplant
Time frame: > 1 year
Cardiac Transplant
Time frame: > 1 year
PPM placement/high grade AV block
Time frame: > 1 year
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