The aim of the study is to evaluate the autonomic failure in Parkinson's disease by clinical, electrophysiological and neuropathological examination.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Enrollment
47
Nantes Universitary Hospital
Nantes, Loire Atlantique, France
Evaluate association between clinical autonomic failure and neuropathological autonomic failure on biopsies.
the main objective is to look after associations between : * anatomopathological signs of autonomic nervous system disorders seen on biopsies AND * clinical signs of signs of autonomic nervous system disorders seen through functional tests or through symptoms indicated by the patient on questionaries.
Time frame: 3 months
Evaluate association between autonomic failure and severity factors in Parkinson's disease
Autonomic failure will be assessed through questionaries on symptoms and through functional tests. Severity factors in parkinson disease will refer to various parameters like patient age.
Time frame: 3 months
Evaluate consequences of autonomic failure on quality of life and sleep quality
quality of life and of sleep will be assessed through functional tests and through questionaries.
Time frame: 3 months
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