Patients with OHS are efficiently managed with long term home-based nocturnal noninvasive positive pressure ventilation (NIPPV). Several NIPPV devices offer the feature of automatically adjusting pressure support (and/or respiratory back-up rate) on the basis of a pre-determined "ideal tidal volume" or "ideal ventilation". However algorithms used to achieve these ideal targets are different among different commercialized devices and the relative efficacy from an algorithm compared to another remains unknown. The main objective is this study is to compare two commercialized NIPPV that have this option
RESMED Stellar-150 (IVAPS mode)versus PHILIPS-RESPIRONICS A30 (AVAPS-mode).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
12
Sleep Laboratory, Grenoble Univeristy Hospital
Grenoble, France
Mean Nocturnal transcutaneous CO2 pressure (Mean nocturnal PtCO2)
transcutaneous CO2 pressure is measured overnight. It is a reliable estimation of arterial PaCO2 to monitor nocturnal ventilation in adults with chronic respiratory failure.
Time frame: 1 night
Mean transcutaneous CO2 pressure during REM Sleep
Time frame: 1 Night
Mean nocturnal SpO2
Time frame: 1 night
Awake arterial PaCO2 after 1 hour of NIPPV withdrawal
Time frame: After 1 night
Micro-arousals/hour of sleep
Time frame: 1 night
Sleep Quality assess by Visual analogic scale (100mm)
Time frame: 1 night
Respiratory residual events detected by NIPPV built-in softwares
Time frame: 1 Night
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