Fitness, Activity and Lung Cancer Study

Oslo University Hospital71 enrolled

Overview

The purpose of the study is to investigate the change in pulmonary function and exercise capacity in lung cancer patients after pulmonary resection. Furthermore, to study the effect of training on aerobic capacity, muscular strength, morbidity and survival. Physical activity level by accelerometers, body composition by DXA and quality of life will also be reported.

Five year after surgery, all included patients will be reinvited to undergo a fourth health excame to study the long-term effects of exercise training on physical fitness, morbidity and survival.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

SINGLE

Enrollment

Conditions

Lung Cancer

Interventions

Physical trainingOTHER

Physical training three times a week for 20 week including endurance and strength training compare to the "as usual" group as controls

As usualOTHER

Controls, not training

Eligibility

Sex: ALLMin age: 30 YearsMax age: 79 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Non smal cell lung cancer * Patient living in Oslo or Akershus county and accepted for lung cancer surgery at Oslo University hospital and Akershus University hospital * were able to read and speak Norwegian Exclusion Criteria: * Mental incompetence or physical disability that makes it difficult to walk on a treadmill * Treatment or medical complications affecting ability to participate in an exercise group * \> 79 years

Locations (1)

Oslo University Hospital

Oslo, Norway

Outcomes

Primary Outcomes

Change in Maximal oxygen uptake (VO2max) from baseline

Change in VO2max from before to after surgery to measure the effect of surgery, and after six months to measure the effect of high-intensity training intervention, and after five years to study long-term effects

Time frame: An expected average of two weeks before surgery (baseline), four to six weeks after surgery, after six months and after 5 years

Secondary Outcomes

Change in Pulmonary function from baseline

Change in pulmonary function from before to after surgery and after the intervention

Time frame: Pulmonary function is measured three times; an expected average of two weeks before surgery, four to six weeks after surgery, after after six months and after five years.

Data from ClinicalTrials.gov

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