Effect of Protein Blend Supplementation During Exercise Training on Muscle Growth and Strength

DuPont Nutrition and Health58 enrolled

Overview

This study will investigate the effects of a soy/dairy protein blend on muscle growth and strength. In sports nutrition and in aging it is important to have healthy muscles. This can be achieved with exercise and nutrition. Consumption of protein following resistance exercise can promote healthy muscle growth and help improve strength. Young healthy men will be studied during a 12 week resistance exercise training program and be given protein supplements every day during the study. The hypothesis is that a blend of soy, whey and casein will induce a greater muscle gain and strength increase than the control.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

QUADRUPLE

Enrollment

Conditions

Muscle

Interventions

Blend

Eligibility

Sex: MALEMin age: 18 YearsMax age: 35 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Stable body weight, healthy, males aged 18-35 Exclusion Criteria: 1. Exercise training (\>2 weekly sessions of moderate to high intensity aerobic or resistance exercise) 2. Resistance Training (\>2 weekly sessions of moderate to high intensity) within the past six months 3. Any orthopedic injury that prohibits participation in the exercise training 4. Significant heart, liver, kidney, blood, or respiratory disease 5. Peripheral vascular disease 6. Diabetes mellitus or other untreated endocrine disease 7. Active cancer (all groups) and history of cancer 8. Acute infectious disease or history of chronic infections (e.g. TB, hepatitis, HIV, herpes) 9. Recent (within 6 months) treatment with anabolic steroids, or corticosteroids. 10. Alcohol or drug abuse 11. Tobacco use (smoking or chewing) 12. BMI range will be (20-29.9 kg/m2) to exclude for Malnutrition (hypoalbuminemia, and/or hypotransferrinemia) and Obesity 13. Low hemoglobin levels (below normal values) 14. Food allergies (including milk and soy) 15. Individuals on a Vegetarian Diet 16. Females 17. Average protein intake \< 0.6 or \>1.8 g/kg per day 18. Taking dietary supplements such as green tea, creatine, ribose, whey or soy protein, etc. within the past 6 months 19. Currently on a high-soy diet or high dairy diet (consuming \>2 servings of soy per day or \>6 servings of dairy)

Outcomes

Primary Outcomes

Change in Muscle Mass

Muscle Mass will be determined by DEXA

Time frame: Baseline, 6 weeks, 12 weeks

Secondary Outcomes

Change in Muscle Strength

Knee Extensor