This observational study will evaluate the predictive value of rapid virological response (RVR) and early virological response (EVR) on sustained virological response (SVR) by stage of liver fibrosis in treatment-naïve patients with chronic hepatitis C genotype 1 initiated on treatment with Pegasys (peginterferon alfa-2a) and Copegus (ribavirin). Patients will be followed for 48 weeks of treatment and up to 24 weeks of follow-up.
Study Type
OBSERVATIONAL
Enrollment
196
Unnamed facility
Bydgoszcz, Poland
Unnamed facility
Bytom, Poland
Unnamed facility
Chorzów, Poland
Unnamed facility
Ciechanów, Poland
Unnamed facility
Dębica, Poland
Unnamed facility
Katowice, Poland
Unnamed facility
Koszalin, Poland
Unnamed facility
Lodz, Poland
Unnamed facility
Mielec, Poland
Unnamed facility
Puławy, Poland
...and 4 more locations
Sustained virological response (SVR) rate, in relation to rapid virological response (RVR) in different stages of liver fibrosis in treatment-naïve patients with chronic hepatitis C genotype 1
Time frame: approximately 3 years
Safety: Incidence of adverse events
Time frame: approximately 3 years
Sustained virological response (SVR) rate, in relation to early virological response (EVR) in different stages of liver fibrosis in treatment naïve patients with chronic hepatitis C genotype 1
Time frame: approximately 3 years
Response rates (RVR, EVR, SVR) according to host/virus/treatment-related factors in different stages of liver fibrosis (F>/=3 and </=3)
Time frame: approximately 3 years
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