Subcapsular Orchiectomy in Men With Klinefelter Syndrome

Odense University Hospital14 enrolled

Overview

Men with Klinefelter syndrome undergo unilateral subcapsular ochiectomy, and the removed testicular tissue is examined for presence of sperm and cryopreserved in small pieces for fertility treatment and scientific purposes. Prior to operation blood samples are frozen in a biobank.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Klinefelter Syndrome

Interventions

OrchiectomyPROCEDURE

The patients undergo subcapsular orchiectomy with basic surgical instruments. The patients are given local analgesia and sometimes universal anesthesia.

Eligibility

Sex: MALEMin age: 15 YearsMax age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Klinefelter * 15-40 years of age Exclusion Criteria: * inability to understand the study

Locations (1)

Fertility Clinic, Odense University Hospital

Odense, Denmark

Outcomes

Primary Outcomes

Presence of testicular sperm

Time frame: Between 1 and 6 months

Secondary Outcomes

Clinical pregnancy rate after ICSI with retrieved testicular sperm

Time frame: participants will be followed for the duration of fertility treatment, an expected average of 6 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.