Measurement of a Systolic Pressure Index at the Toe After a Walking Test

Centre Hospitalier Universitaire de Nīmes50 enrolled

Overview

The main objective of this study is to evaluate the concordance of the variation in systolic pressure indices measured at the toe and ankle after a walking test in healthy volunteers.

Our secondary objectives are: * to evaluate the concordance between left- and right-side measures: systolic pressure indices measured at the toe after a walking test (healthy volunteers) * to evaluate the concordance between left- and right-side measures: systolic pressure indices measured at the ankle after a walking test (healthy volunteers) * to evaluate the concordance of the variation in systolic pressure indices measured at the toe and ankle during the recuperation phase after a walking test (5 and 10 minutes after end of walking test) in healthy volunteers

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Good Health

Interventions

Ankle firstPROCEDURE

1. Brachial blood pressure on both the left and right (BBP-LR) sides is measured, as well as at the left and right ankles (BPA-LR). 2. A 15 minute walking test (WT) is performed. 3. BBP-LR and BPA-LR are re-measured. 4. 2 hours of rest. 5. BBP-LR and the blood pressure at the left and right big toes (BPT-LR) are measured. 6. WT is reperformed. 7. BBP-LR and BPT-LR are re-measured.

Toe firstPROCEDURE

1. Brachial blood pressure on both the left and right (BBP-LR) sides is measured, as well as at the left and right big toes (BPT-LR). 2. A 15 minute walking test (WT) is performed. 3. BBP-LR and BPT-LR are re-measured. 4. 2 hours of rest. 5. BBP-LR and the blood pressure at the left and right ankles (BPA-LR) are measured. 6. WT is reperformed. 7. BBP-LR and BPA-LR are re-measured.

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * The subject must have given his/her informed and signed consent * The subject must be insured or beneficiary of a health insurance plan Exclusion Criteria: * The subject is in an exclusion period determined by a previous study * The subject is under judicial protection, under tutorship or curatorship * The subject refuses to sign the consent * It is impossible to correctly inform the subject * The subject is pregnant, parturient, or breastfeeding * The subject has a contraindication for a walking test * Presence of mediacalcose objectified by a Doppler examination of the anterior and posterior tibial arteries, performed on the test day * Known history of cardiovascular disease * Poorly controlled diabetes or hypertension * Neurological, muscular or rheumatic pathology contra-indicating a walking test * Acute transient infection (cold-rhinitis, flu, etc.)

Locations (1)

CHU de Nîmes - Hôpital Universitaire Carémeau

Nîmes, France

Outcomes

Primary Outcomes

Difference between brachial and ankle blood pressure

Time frame: Before effort test (minute -15, day 0)

Difference between brachial and ankle blood pressure

Time frame: After effort test (minute 0, day 0)

Difference between brachial and toe blood pressure

Time frame: Before effort test (minute -15, day 0)

Difference between brachial and toe blood pressure

Time frame: After effort test (minute 0, day 0)

Secondary Outcomes

Brachial blood pressure, left arm

Time frame: Before effort test (minute -15, day 0)

Brachial blood pressure, left arm

Time frame: After effort test (minute 0, day 0)

Brachial blood pressure, left arm

Time frame: After effort test (minute 5, day 0)

Brachial blood pressure, left arm

Time frame: After effort test (minute 10, day 0)

Brachial blood pressure, right arm

Time frame: Before effort test (minute -15, day 0)

Brachial blood pressure, right arm

Time frame: After effort test (minute 0, day 0)

Brachial blood pressure, right arm

Time frame: After effort test (minute 5, day 0)

Data from ClinicalTrials.gov

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