Can Fish Oil and Phytochemical Supplements Mimic Anti-Aging Effects of Calorie Restriction?

Washington University School of Medicine56 enrolled

Overview

The purpose of this study is to determine if a combination of 10 nutritional supplements provide health benefits that are consistent with protection against age-related disease. All supplements have been shown in previous studies to have health benefits when administered alone. The hypothesis is that 6 months of taking 10 nutritional supplements each day will provide beneficial changes in healthy related measures.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Healthy Volunteers

Interventions

SupplementDIETARY_SUPPLEMENT

Participants in this group will take the following nutritional supplements on a daily basis: curcumin, fish oil, resveratrol, sesamin, Acetyl-L-carnitine, lipoic acid, green and black teas, quercetin, pomegranate, cinnamon bark.

Eligibility

Sex: ALLMin age: 40 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * age 40-60 yr * body mass index of 21 - 30 kg/m2 * sedentary to moderately active * eating a typical US diet Exclusion Criteria: * history of any chronic disease other than mild osteoarthritis * use of medications other than occasional use of non-steroidal anti-inflammatory drugs, antihistamines, antacids or laxatives * use of nutritional supplements * smoking * alcohol intake greater than two drinks per day for women and three drinks per day for men

Locations (1)

Washington University Medical Center

St Louis, Missouri, United States

Outcomes

Primary Outcomes

Carotid-femoral pulse wave velocity

Time frame: Baseline and 6 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.