Safety and Performance Evaluation of Tulip Device in Healthy Overweight and Obese Volunteers

Inclusion Criteria: * 21 ≤ Age \<65 years * 30 \< BMI ≤ 35 kg/m2 * Healthy without any medication; * No history of weight reduction of more than 5% of total body weight in the past 6 months; * Normal blood count and chemistry; * Hemoglobin level over 11; * At least 3 bowel movements per week; * Subject declares that he/she is able to go through gastroscopic examination; * Subject is able and willing to give informed consent and follow protocol procedures. Exclusion Criteria: * Any history or evidence of significant cardiac, renal, neurologic, metabolic, pulmonary, gastrointestinal, hematologic abnormality, chronic hepatic disease or any other disease which in the judgment of the investigator would interfere with the study or confound the results; * History or evidence of any active liver disease. (abnormal liver functions: \>1.5 times upper limit); * History or symptoms of thyroid disease which is not controlled by medication; * Abnormal gastrointestinal findings: Diaphragmatic hernia \> 3 cm; Active peptic ulcer; Erosive gastritis; Gastric outlet obstruction; * Subject with IBD * Significant swallowing disorders; * Past history of any gastrointestinal surgery (excluding uncomplicated appendectomy); * Malabsorption disorders. * Is taking medications that reduce gastric acidity * Currently using pharmaceutical agents or food supplements for weight loss; * History of or current eating disorder such as anorexia or bulimia or compulsory overeating. * History of food Allergy; * Subject with poor venous access; * Is taking chronic aspirin or other non-steroidal anti-inflammatory agents, or other medications known to be gastric irritants; * Have any coagulation problem and/or taking any anticoagulant medications; * Evidence of current malignant disease; * Have history of any acute disease (viral, bacterial, pain, accident) in the last 6 weeks. * Female subject who are breastfeeding or have a positive pregnancy test at screening or at any time during the study; * Inability to give written informed consent; * History of alcohol or drug abuse within 6 months of screening; * Mental disorders; * Currently participating in an ongoing clinical study * Any reasons making the patient a poor candidate in the opinion of the investigator.