Safety and Efficacy of Fibrin Sealant Grifols (FS Grifols) During Parenchymous Tissue Open Surgeries

Inclusion Criteria: * Hemoglobin (Hgb) ≥ 8.0 g/dL at Baseline (within 24 hours prior to surgical procedure). * Require elective (non-emergency), open (non-laparoscopic), hepatic resection (anatomic or non-anatomic resections of at least one anatomical hepatic segment, or equivalent tissue volume). * A target bleeding site can be identified. * Target bleeding site is identified on the cut raw liver surface (resection area). * Target bleeding site has moderate bleeding according to the Investigator's judgment. Exclusion Criteria: * Require hepatic resection due to trauma. * Infection in the anatomic surgical area. * History of severe (e.g. anaphylactic) reactions to blood or to any blood-derived product. * Previous known sensitivity to any Fibrin Sealant Grifols component or any Surgicel® component. * Females who are pregnant or nursing a child at Baseline (within 24 hours prior to surgical procedure). * Receiving an organ transplant during the same surgical procedure. * Undergone a therapeutic surgical procedure within 30 days from the screening visit. * A target bleeding site cannot be identified. * The target bleeding site has a mild or severe bleeding. * Occurrence of major intraoperative complications that require resuscitation or deviation from the planned surgical procedure. * Application of any topical haemostatic material on the resection surface of the liver prior to application of study treatment.