Long Term Evaluation of Sevelamer HCl vs. Calcium-based Phosphate Binder in the Treatment of Hyperphosphatemia in Hemodialysis Patients

Inclusion Criteria: * Males or females aged between 18-70 years old * Subject with hyperphosphatemia (5.5 - 8.5 mg/dL) at both WK(-2) and WK0 * On stable TIW hemodialysis for 3 months or longer Exclusion Criteria: * Patients with hypercalcemia (corrected serum calcium \> 10.5 mg/dL) * Any of the following abnormalities: ALT or AST \> 3X ULN; iPTH \> 1000 or \< 150 pg/mL * History of dysphagia or swallowing disorders * History of GI motility disorder or GI bleeding within 3 months prior to entry