Exploratory the S-1 + Paclitaxel Chemotherapy for Creating the Operation Chance in the Patients with Unresectable Gastric Cancer
To assess the effectiveness and safety of S-1 + Paclitaxel for the peri-operative chemotherapy in Chinese patients with unresectable gastric cancer, so as to further find out the optimal protocol for the peri-operative chemotherapy in the patients with gastric cancer.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
60
Dose of S-1: 60mg bid,Twice daily (after the breakfast and supper) for two weeks, and then suspend for one week. Dose of Paclitaxel: 150 mg/m2, iv, 3h, at D1
Zhejiang Cancer Hospital
Hangzhou, Zhejiang, China
RECRUITINGradical resection rate
radical resection rate
Time frame: 3 months
Adverse Events
Number and degree of Adverse Events
Time frame: 6 months
reaction rate
the reaction rate of chemotherapy
Time frame: 2 months
overall survival time
the overall survival time
Time frame: 3 years
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