The purpose of this study is to evaluate effect of moxifloxacin on QT/QTc interval in healthy male subjects. Moxifloxacin is a positive control drug used in QT study. In this study, moxifloxacin 400mg and 800mg will be used, to get information on effect of moxifloxacin on QT/QTc interval.
The purpose of this study is to evaluate effect of moxifloxacin on QT/QTc interval in healthy male subjects. Moxifloxacin is a positive control drug used in QT study. In this study, moxifloxacin 400mg and 800mg will be used, (therapeutic and supratherapeutic doses) to get information on effect of moxifloxacin on QT/QTc interval in healthy Korean male subjects.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
39
Seoul National University Hospital
Seoul, South Korea
QTc (QTcF, QTcB, QTcI)
QTc (QTcF, QTcB, QTcI) * QTcF (Fridericia-corrected QTc) * QTcB (Bazett-corrected QTc) * QTcI (Individual-corrected QTc) QTc change: the largest time-matched, baseline-adjusted least squares mean difference time-matched, baseline-adjusted least squares mean difference
Time frame: Day1 and Day2 of each periods(3 periods)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.