In addition to a genetic susceptibility, the immune system and the intestinal microbiota, diet is hypothesized to be an important factor in the onset and progression of Inflammatory Bowel Diseases (IBD). Further insight in factors affecting disease activity may contribute to targeted interventions improving disease burden and healthcare costs for these patients. However, well-designed studies exploring the role of diet in the development of exacerbations are hardly available. The investigators hypothesize that differences in dietary patterns affects the intestinal microbiota composition and thereby contributes to the development of exacerbations in IBD. Furthermore, a subgroup of patients suffers from malnutrition, although the exact prevalence is unknown since simple noninvasive screening tools have not been validated for IBD. The investigators hypothesize that malnutrition is frequently present in IBD patients and associated with dietary intake and disease characteristics.
Study Type
OBSERVATIONAL
Enrollment
273
Maastricht University Medical Center, Division of Gastroenterology/Hepatology
Maastricht, Limburg, Netherlands
The primary aim is to study the association of dietary patterns with disease activity in a consecutive cohort of IBD outpatients
Time frame: 2 years
To characterize intestinal microbiota in IBD patients with different dietary patterns
Time frame: 2 years
To characterize the intestinal microbiota in IBD patients in remission developing an exacerbation during follow up
Time frame: 2 years
To investigate the stability of the intestinal microbiota in IBD patients remaining in remission during one year follow-up
Time frame: 2 years
To study the prevalence of malnutrition in a consecutive cohort of IBD outpatients
In a subpopulation of the present cohort (n=300) the nutritional status will be investigated
Time frame: 1 year
The study the association of disease characteristics and dietary intake with the prevalence of malnutrition in a consecutive cohort of IBD outpatients
Time frame: 1 year
To study the sensitivity and specificity of the SNAQ / MST as malnutrition screening tool in IBD outpatients based
Time frame: 1 year
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