The Effect and Prognosis of Different Operations on Varicocele - a Single-center Clinical Study

First Affiliated Hospital, Sun Yat-Sen University1,000 enrolled

Overview

The purpose of this study is to determine whether high ligation of spermatic vein by open operation and microsurgery for patients with are effective in the treatment of varicocele and to determine which surgical option is better.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

1,000

Conditions

Varicocele; Male Infertile;Varicocelectomy

Interventions

open operationPROCEDURE

high ligation of spermatic vein by open operation

microsurgeryPROCEDURE

high ligation of spermatic vein by microsurgery

Eligibility

Sex: MALEMin age: 10 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 1.infertile patient suffering from varicocele 2.severe varicocele patient with obvious symptoms 3.adolescents suffering from severe varicocele with or without orchiatrophy Exclusion Criteria: * 1.varicocele patient with abdominal infection 2.varicocele patient who has massive adhesion of pelvic tissue due to pelvic surgery history 3.mild varicocele 4.varicocele patient has no obvious symptoms if has have born children, suffer from idiopathic azoospermia，or their partner can't bear children

Locations (1)

First Affiliated hospital，Sun Yat-Sen University.

Guangzhou, Guangdong, China

Outcomes

Primary Outcomes

the quality of semen and the level of sexual hormone

The semen analyses and were sexual hormones determinations conducted before and three and six months after surgery.Then the quality of semen and the level of sexual hormone before and after surgery were compared.

Time frame: before and three and six months after surgery

complications

the complications such as recurrence, hydrocele,orchiatrophy and wound infection were assessed one, three and six months postoperation. Color doppler ultrasonography and physical examination are the main methods to assess the complications

Time frame: one, three and six months postoperation

Secondary Outcomes

If there was pain, visual analogue scale,Numerical rating scale and verbal rating scale would be used to evaluate pain intensity. pain intensity

If there was pain, visual analogue scale,Numerical rating scale and verbal rating scale would be used to evaluate pain intensity.

Time frame: before and one,three and six months after surgery

Data from ClinicalTrials.gov

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